Sounds much like the difference between traditional and digital comics to me 
Live instruments are warmer, less perfect, more humane, even awfully precise one, or the one trying to be dead cold... thereās life in the tiny imperfections.
Meanwhile, electronic is colder, more mechanical. Even programmed (or blatant) imperfections, or sampled instruments sound inhumane in intent. Something slightly fascinating but hard to trust in its sincerity.
I like both for different reasons though, each better fit a kind of mood I guess.
But thatās just me, and I might be weird...