My current comic is not political. It takes inspiration from USSR sci-fi kidlit (which is something I grew up on) so there is an... ah... undercurrent of socialism in it (it's a utopian society where everyone is equal and gets what they want as long as they're willing to reach for it, and there is no money, although people do barter skills, knowledge and crafts/objects to obtain something someone else has. There is a whole galactic economy centered around knowledge exchange. Generally in USSR kidlit they just kinda... took it if they needed it and returned it after they were done, and the M-word never ever figured, unless a villain was involved). But for the most part the comic is supposed to be my happy place so I'm staying away from anything super frustrating (unless you count character diversity as "frustrating" or "political" I guess. Sorry for writing characters similar to me and my friends growing up (and my children, going forward)?).
My comic that I'm currently scripting though IS very political. It's about a young Asian-Canadian man (adopted by a white family - dw they're model parents) in an alt 1990's where demons and magic are common knowledge. He grew up in a church (his father is a pastor) and trained as an exorcist before finding out that, ooops, he's actually a half-demon through his biological parents and therefore "evil incarnate from birth". It's about identity and having the right to define who you are. The MC does spend a lot of time fighting demons and evil supernatural things but half the time they point to a human behind the whole thing.
And the novel I'm writing is about a young woman who is the illegitimate daughter of a galactic Emperor who goes to court to try and take over the empire. The empire is based on debt from space colonization thousands of years ago when humanity had no choice but to escape Earth, which created a class-based society (and is a less-than-subtle nod to the current politics of socioeconomic inequality). At the same time she's doing that, there is a socialist revolution being plotted by the other protagonist (originally it was a democratic revolution, but I wanted to make it a little bit more interesting for the reader and make them have to grapple with the choice between socialism and imperialism. I try to not present either side as good or evil and both have good and bad people on both sides). So this story LITERALLY is about politics.
ETA: I think spec fic makes the perfect vehicle for examining politics, even more so than political cartoons and strips... because spec fic has the potential to distance the reader enough from the real world that they don't get suckered into their biases, but close enough to humanity that at some point in time, they go... wait a minute... if I feel this way about a fictional society, why the hell do I not feel the same about my own, when the issues are so similar?