I've got a good number of explicitly political comics in my series, which is essentially a series of jokes I find funny and very often I find political things funny, so I make a comic about them. Honestly, I'm surprised I haven't triggered even worse political discussions with my comics; I've been assured countless times that the second a comedian delves into politics, everything becomes a hellhole. But I release a political cartoon one week and it incites some laughter and some hurt feelings from the target(s) of ridicule, then the next week I do a comic about video game hijinks and everyone's getting along again.
Though I have slightly adjusted what subject matter I make a comic about now. I'll avoid very recent subjects, not because of any reservations about jokes being "too soon," but because it really dates that specific comic and people reading back on my stuff won't have the context to enjoy it anymore. Most of these comics are on my personal website - by the time I was reuploading my earlier comics to Tapas and Webtoon I left them off because they just weren't timely anymore. Also, with how quickly the news cycle moves these days, an idea I'll have might not even be relevant anymore by the time I release the comic (this can happen within 2 days),
The way I see it, there's two explanations for how I've avoided significant backlash: 1) I'm a nobody and no one's leaving my readership over political opinions because no one's reading in the first place, or 2) I'm so hilarious that people don't care about my political opinions because I still make them laugh.