To answer your title: yes, you should make that comic :]
Do keep in mind that for people to want to read it, you have to have the characters doing stuff. People have suggested some great ways to approach this already, and I don't have much to add to that.
But the act of actually starting your comic, even if you're not sure what they'll do, will probably help you figure out how you want to proceed with your comic making journey. I tried drawing my first comic without any idea what my characters are actually going to be doing, and I gave up after 5 pages because I couldn't think of what to do next XD But I don't regret it at all :]
Drawing comics is a hugely time-consuming pain in the butt, and if you yourself get tired of drawing your comic, that's probably the only thing that will convince you that you need to go back to the drawing board and develop an idea that you're excited enough about to push through that tedious drawing process to make a reality :]