Thanks so much for your thoughtful response. I truly appreciate it. I hope this feedback helps in return!
A) A scientist named "Blondie", 60 years ago, was lost to a pocket dimension alongside his coworkers. These scientists were conducting dangerous experiments on the fabric of reality itself. Reality itself is just a program, and can be manipulated by it's source code. It has a defined beginning and ending, and then the timeline reboots itself to repeat the cycle. However, excessive tampering can cause corruption to the laws of nature. This world is unlike our own, because this information is all common knowledge in schooling.
Blondie eventually finds a way to communicate with the modern-day scientists back home. He reaches out to Eleanor, the first female Head Researcher, seeking a way to escape his fate.
At first glance, the plot is a general warning against meddling with things you don't have enough knowledge about. On a deeper level, this appears to be a story about recognition and understanding. The characters want their ambitions recognized and their feelings to be acknowledged. The setting brings it all together because you can't judge reality without understanding how it works. You can't understand a person without knowing their history, without knowing what happened to them (say, an explosion, for example).
B) I hope that Eleanor can come to peace with her grandmother. Maybe there will be a scene where she talks to her grandmother one last time (through reality bending shenanigans). Through this interaction, she no longer sees her relative as a haunting memory of the past, but as a person, someone with her own tragedy and losses. I want to see Blondie grow up and mature, and escape the confines of childhood. A metaphorical way for him to "escape" the pocket dimension.
C) Your use of flashing images is unique. You mostly use it to show quick flashbacks (or memories) with little context, so the reader doesn't spend too much time on each picture. It fits well into the idea of reality-breaking.
Eleanor has some great deadpan moments. I really enjoyed the parallels between Blondie and Eleana's fear of exposure. They're both afraid to let others know too much about themselves. You've clearly spent a lot of time developing their character arcs.
D) "Access Granted." Sounds more sci-fi!
In the first chapter, I thought the message from Lucy was a little generic. I think a more specific message would have helped to immerse me. You tend to have a lot of panels only showing a character's face and shoulders. Your comic is rather dialogue heavy, so this is understandable. However, you're not writing a book! I'd like to see more establishing backgrounds to give readers a better sense of space and dimension.