If your comics are more plot-driven and meant for more mature audiences, just go with that since it's what you've been putting your time and passion into. :] That's all that really matters. If you're genuine that's usually what resonates well with the readers, I think. Sure a there's comics that are slice of life or gag-a-days that are super popular with great connection with the readers, but I think that's still attainable across the board. It may take time and effort to build up your subscriber base, but it will probably be more meaningful to you as well than if you started a slice of life just for the sake of making a slice of life. :3
Everyone has their own likes and dislikes, so it's good that you're conscious of the community, but I say go for what you love and want to share. My own comic was a creative outlet for myself with no thought about numbers when I started it and it felt great just to be drawing for myself. :] Who knows, maybe you could be a success quickly or steadily grow your subscriber base while advertising yourself on social media and such too. You can also stay connected with readers by posting pics and messages on your profile/wall or do livestreams too.