It’s true, there’s honestly not a lot you can do about that. It was driving me crazy at first, too, but then I realized it was because I kept zooming in to examine the details and that the readers weren’t really going to be doing that.
I also decided to offer larger, higher res versions posted on my Patreon page that looked the way I wanted them to look, so higher quality pages could be a gift to my Patrons. Maybe you could post versions of the comic that you like better on tumblr or instagram and let your readers know that’s an option if they want them.