Oh man, absolutely! Several alternate universe ideas and, as it would come to be, the main comic I'm working on is an alternate universe idea I just couldn't put down~ I've written a couple of stories about parallel dimensions and universes-in-tandem with one another... it's really awesome to open up your characters' psyches to a near-endless realm of possibilities. It helps so much to learn more about how they react in a wide variety situations/times, too.
But it's especially interesting to see how others' develop ideas based on throwing their characters into other timelines -- just as you imagine moving yours from first century Judea to modern-day US. THAT would be such a mind-bender, hah^^ Culture and time clashes to the max!
Wondering on the small, finicky things is just as intriguing, too (what kind of cell phone would they buy? Sneakers or boots? Would they be drawn to twitter or facebook more??) X]