I like uploads with more panels. However I am fine with those who divide their weekly chapters by two parts and upload more often. It's fine to even divide the chapters by 3...I think 4 would be a lot.
When people upload single page chapters I tend to get dizzy from scrolling so much, this is mainly when I marathon a series. I am also less likely to comment on each page released. I think I wouldn't mind if I was getting a single page each time if I was already updated, that's probably when I'll start commenting every page, hah xD. Although, one advantage to single page uploads is that people will come across your story more.
But definitely upload whichever way your time allows you to perform the best :).