Of course, it depends on what kind of comic you're going to do. For example, in my webcomic Bet on it, as it is a slice of life, it uses real names that I search in baby websites XD also, they're related to the character's origins/nationality/idon'tknowhowtoexplainmyself (???) like Hana, Noora, Hector... (although Bet on it isn't placed anywhere really). But, in my upcoming webcomic that I'll start working on this summer, as it's placed in nowhere, the names are totally made up: Ho, Giu, Za... (ok, they kinda have meaning. Giu comes from budgie > gie > giu because when I first drew this character when I was working in the design totally reminded me to a parakeet hahahaha. Ho and Za are also other known words cropped from spanish and english but I won't say the original words because it might be spoily).
And also, looking for a name that suits the character because of its meaning is also a really interesting thing to do!