Before you do ANYTHING, go to your bookshop or library and get yourself a copy of "Making Comics" by Scott McCloud. Read the whole thing. It will teach you so many vital things about comics.
Do test pages or test panels first, or draw some sort of short, self-contained comic (say four pages or a 20 panel scroll) so you can get all your beginner mistakes out of the way and not have them messing up those vital early pages that will be the first impression a reader gets of your comic. You WILL make beginner mistakes, because comics are a really complex medium with so many moving parts, so make your mistakes in a safe environment.
You'll need to decide if you're going long scroll or page by page. I'd advise long scroll to anyone who isn't really keen to also learn about print specifications and making a print comic. If you want to make a print comic, you'll need to learn about trim, bleed, safety zone and make the whole thing at 300+ dpi, so it's a whole lot of extra fuss for a format that might put off some readers. Long scroll is a popular and accessible format I'd recommend for people starting now.
Now on the drawing... honestly it's hard to advise without seeing what your current level is like. Get a decent graphics tablet that works for you, and don't be scared to customise it. Some people like a shiny surface, others like a rough one, some people can't draw without a screen, others are perfectly fine without one, some people can only draw on a big tablet while personally I've never used anything bigger than a "medium" wacom in the 15+ years I've been making comics and have never had RSI or wrist issues.
I generally recommend Clip Studio as the software because it can handle all of panels, drawing, inking, colours and even speech bubbles and text or importing 3D reference, patterns etc. The more expensive Clip Studio EX isn't vital, but the page management is very useful if you draw page-by-page comics.
The key thing with drawing comics is to come up with an efficient pipeline for making your pages or episodes that balances "looks decent" with "I can make an update every week or two". It's easy to fall into the trap of making the art style way too fancy, neat and detailed and then not being able to maintain regular updates or burning out. In a contest between a comic that looks amazing but only updates every few months, and a comic that looks okay and updates every week, the one that updates more will end up with more engagement.