In my opinion, the best thing to do is to not follow someone who follows you UNLESS you are really interested in their comic and would read it even if they were not reading yours, (AND)/OR you know the person well enough and from what you know, you want to give them an extra chance even if the comic is not your style, etc.
Following a follower's comic just because it exists will potentially bring unsubs, but also awkwardness. You may feel obligated to read it, to keep subscribed to it even if you don't read it and the person updates all the times, you may feel bad if you unsub, etc
I keep a separated list of comics I want to read later and put these in this list. I think it's a good way to not clog up your comic notifications and still keep track of comics you want to give a chance to.
From time to time, I also remove comics from my subscription list if I don't read them and put them in that other list.