I've been drawing on an iPad for like 7 years now. Idk if I would have pulled off comics on my old iPad (I was literally drawing with my finger in Procreate), but I comfortably pull them off now. The only thing I do on the PC is putting numbers on the pages of Bestia's Wrath, and upload the pages. I transfer them through Dropbox.
I used to fully do Bestia's Wrath in Medibang, but I have switched over to Procreate for everything except the panels. The Lost Firstborn is made the same way, with panels done in Medibang and the rest done in Procreate.
So yeah, you absolutely can use just an iPad!