I think it depends on how many eyes you get on your work. If you want to grow, you're going to run into people who don't like what you do. And as your readership becomes bigger and less intimate, people start to interact with your work differently --
Imagine if your friend is telling you a story. You're probably not going to tell him "haha wow that story sucked!!" or talk on twitter or facebook about how bad your friend's story was, because you're not a rude person. But if you come out of a movie that sucked, it doesn't feel as weird to talk about how much that movie sucked on your social media, or to tweet at the official Marvel twitter account that they need to get their act together.
If you get really popular, people stop seeing you like a friend telling a story, and more like a company making a movie. Something shifts. And once that happens, yeah, I think its inevitable to get some people who are rude about your work.
But I think a lot of us haven't hit that level yet. I've encountered people who dislike my work, and I've seen people complaining about it in their own space -- seeing it get brought up on some other forum I'm not on, and folks talking about things they didn't like, or a disparaging comment on a review someone did of my work. I wouldn't call it bashing, but if that's what you mean, then yeah, I think it's inevitable that with a readership will come people who eventually talk about not liking your comic on the internet.
But if you mean people being rude to you, then I don't think they automatically come out of the woodwork as soon as you have readers -- though it really depends. I've only had one or two people actually speak to me unkindly -- most of the critique or problems folks have had with my work have been things they've broached very thoughtfully with me! I know some folks have had less luck and run into more rude folks, but it's a lot less of an inevitability when you're not a big name.