I wouldn’t do anything that couldn’t go to print so what I did when I was doing a featured comic with webtoons was I just sliced up my regular pages. And now I’m putting out collection with a publisher this year without having to pull my hair out piecing it all together.
Honestly though the only audience I’ve ever really heard complain about “horizontal” comics were the Tapas and Webtoons audience. My regular audience has never complained about it or even brought it up as a suggestion as far as I can tell.