not sure if this is any help, but I used to do a comic print from school computers, as well as using my home, which is where I found out, that the programs you use to print can vary, but depending on the printer; if printing. to make sure that either the program reads into the printer book format or remember to lay out first page then last page till you meet in the middle, if that makes any since.
so basically it's cover- back cover
inside would be the opposite last page- first page so it's prints back. not sure if that makes since at all! but it's something I had to deal with in school when making a printed comic-zine type thing. and we had basically normal printers, so I had to turn the paper over so it would print the other side.
otherwise I've used an old version of publisher, it's not to hard. but I use photoshop for any editing then export to a printing program. normally 300 dpi is good, I use 600dpi
not sure if that was any help, but either way sounds like a lot of fun! I hope it goes well!