- interesting or original plot
- characters that are cute/attractive
- amazingly detailed/realistic visuals
All of these things can be good things, so if you're asking "do these things increase the chance of catching a reader's interest," then I would say, yes! If you're asking if you HAVE to have these things, or if you're asking which one is best or more important, then I agree with @CatharsisGaze - different elements are better for different stories and will attract different people. You don't NEED realistic visuals to attract readers -- sometimes simple or cartoony art works better for the story -- but if detailed art is something you're good at, then those visuals will attract the readers who love that kind of art.
- randomness in general
- relatability
I think looking at content can be looking at the wrong thing. For example, Owlturd Comix are "relatable"-style comics about failing at life, and they're popular, so it's easy to assume that the reason those comics do well is that they're relatable.... but I don't think that's true. Owlturd Comix do well because they have good comedic timing and really well-crafted visuals. Joking about life beating you up isn't what makes Owlturd Comix funny -- it's because the joke is well-told.
Randomness is similar -- Invader Zim got a generation of kids to burst out laughing at "to make room for the cupcake!" and to think that means random non-sequiturs must be what makes it funny. But there's actually a lot of writing, timing, and delivery that goes into making Gir's outbursts funny when you're watching the show. Randomness isn't always funny all by itself - it's not as funny when people just yell "TACOS" at a random time.
Basically, it's easy to make the mistake of seeing a funny joke about random things, and thinking "random things" are the key to being popular, or seeing a funny joke about relatable things, and thinking "relatable jokes" are the key to being popular. But those aren't the important part! The key is that the joke was funny!
I gotta ask - is critique really what you're looking for? Your comic looks more like it's a thing you do for fun with characters you and your friends made. It's okay to have a comic that's just fun random silliness between friends! But it's going to be hard for people who don't know you or your characters to get into -- I can't tell what's happening in most of the comics until I read the description. So it depends on what you want your comic to be -- if you want to make jokes for your friends, things that make you guys laugh, and put it up in case someone else likes it, then do that! But if you want to entertain a wider audience with your comic, I think it would be good to think a lot about clarity, how to make it so that people can tell what's happening, and what your characters are doing and thinking, even when they don't speak understandably.