Yes, I get this on occasion, usually with things I've never watched or heard of, and my main character used to be compared to Levi from AoT SOOO often, though that's starting to become less frequent.
I try not to let it bother me since most of the time it's meant to be a compliment or little more than an observation. Sometimes people say things just to say things - to be nice and leave a comment. Unless they're directly ACCUSING you of ripping off something, then that's obviously a different situation.
Also @dojo is right, if anything it means you've piqued the reader's interest. If you don't react with too much bitterness (or at least don't react at all) then they might just stick around and get into your comic for the unique story it actually is. XD
Basically, I recommend taking this with a grain of salt and a bit of good humor when it happens, because it may definitely happen more than a few times.
Though I will say what bothers me even more is getting said comparison multiple times from the same person. I'm sitting there thinking, "Okay, let it go. Still wasn't inspired by that." XP