I guess it's not a dilemma so much as a question of preference, so to preface:
I recently had my producer for a different comic ask why several comic panels had our MC without a nose, which, if anyone has read my webcomic, would know that I do this for stylistic purposes (mostly for comedic effect) to exaggerate facial expressions and let the mouth and eyes be the focus. It's often used in manga, which is a very early influence on my own art.
So the question is, does it throw you off, as a reader, when a character is noseless? I'm really curious to see, especially people who read more western comics than manga, what effect that has on a reader.
EDIT: whoops, forgot "out" in without.