If I'm understanding this correctly, it should be the same thing.
Your series with the most subscribers will be used to count towards the ad revenue/ tipping threshold needed, but all other series' subscribers don't count.
If you have 75 subscribers for one comic and 200 subscribers for another for a total of 275 subscribers (assuming that all subscribers are subscribed to one or the other but not both), you get ad revenue because your most subscribed to comic has more than 100 subscribers needed to activate ad revenue, but not tipping because, although your total subscriber count is above the 250 subscribers needed, your most subscribed series is still below the 250 subscribers needed.
I hope that could clear something up.