Oh boy, writing is hard.
Just a few things to keep in mind.
Makes the 'stakes' clear and important.
Give your characters flaws and shortcomings, then present them with problems that challenge those traits.
Always ratchet up the problems. Pile them on.
Overlay (or is it underlay) some subtext. For example, you comic might be a guy travelling the world, meeting people, hooking up, seeing the sights, trying new things, fun for him yes, but for a reader? Meh, nothing new. Why not make it so he's abandoned his wife and kid, all of a sudden, there's conflict. Now all that fun stuff he's doing is tainted.
Someone mentioned irony before. Brilliant.
Just remember, this is fiction. Pretty much life with all the boring bits taken out. So if you're worried, just cut out anything 'normal' or mundane. Even if you're writing a drama, dialogue and actions don't have to be replications of real life. Make it tense, build in some mystery, introduce characters the audience will love to hate.