That's subjective for me (especially since I'm not done with Season 1 yet) lol. But I'll pick my favorite two lines since it's a tie.
"Friend let me tell you something... to me you look no different than that guy, or that guy... or that girl! But that's okay because you have something they don't have. A heart. Arguably the most anime part of a character". - Naota Nakaoka, That Stick Figure Isekai
And another when Naota and Quincy are trying to save D and Nancy, and they question the consequences of the situation. Naota's like "Well we got nothing to lose since we're pretty much working for Heaven" and Quincy's straight up like "Yeah, but my feet do". Naota's like "Huh" and Quincy asks "Say, do you know how to walk in high heels because I don't".
I was afraid that the scene could get expositiony, but I was so happy that I was able to get the idea that they'll just reincarnate again into bodies that they may be uncomfortable in.