Well most of the changes happened because as I was outlining, I developed an interest in Cyberpunk, when previous ones had either been more like Silent Hill / Resident Evil. And my short story style overall is pretty different. So this meant plot changes that I couldn't avoid, which meant basically writing the original second half out of continuity.
So for example, Susie, Samantha, Rachel, and Jkovo were never born in the main continuity, but remain around in alternative continuities. Incidentally the wars that happened in this alternative continuity was of a much larger scale as well. There were even Lunar Penal Colonies in that continuity. This continuity also assumes France and Japan didn't take over the US, or that the US didn't split off into various nations in their own right.
I hadn't considered whether Millie, Aldiel, and Dantino, or even Hemato would still exist in that continuity however. Which means the older timeline would have been without cyborgs as well.