Drama is a genre that deals with generally non-epic situations in a serious context, in a tone more likely to inspire sadness than laughter. Nevertheless, the drama etymologically evokes action. Generally, a drama is based on a scenario approaching with as little humor as possible a serious theme (death, misery, rape, drug addiction…) which can be painful, revolting; an injustice. It can be inspired by history (with themes like WWII as in She Was Called Sarah) or current events.
Also Drama =/= Tragedy.