I went from having my novel listed as sci-fi, which is among the least popular genres here, so any likes sent my story close to the top. Then I heard some advice to choose genre based on what kind of books it matches in general looks/tone, and I felt like the LGBTQ+ section was a better fit. It's among one of the most popular genres, so it's rarer for me to get to the top of the rankings, but I also feel like it has more traffic.
You might end up doing the opposite of kneecapping yourself! Though I have found that novels on this site aren't really that competitive. I don't know how this would translate to comics. Either way, you can always change back!