I'd skip straight to the talk portions.
Unless it was just a few songs- like the 'Cracked' podcast does two or three songs per 90 minute episode and they usually have something to do with the theme of the episode and the host explains their importance. 'This American Life' also does this, but same thing where it's MOSTLY talking and then one on-theme song as an interlude between talking.
But yeah, if it's not adding to the show or at least relevant to the show, I don't think I'd want to hear music. In fact you might be limiting your audience since you'd be making a venn diagram of 'people who like comics' and 'people who like the music I like' and only reaching the overlap rather than the whole comic liking circle.