honestly, yeah, id still read. it makes v little different to me; i sub to a fair amt of comics and the way i am i forget about them until theyre there again - so im not sat drumming my fingers unless its something im Really hooked on. and then, the waits worth it. my very favourite webcomics barely ever update but when they do catch me shouting from the rooftops.
on the other hand, a regular updating pace can give you a familiarity with readers - oh, look, its thursday, theres that comic again. they get to know you & that youre reliable, and that could pull you more subs from the 'fresh' page or the like.