well, you are a safer bet to a lot of publishers if you already have an audience online, although it depends on the size. there's been a lot of novels, even comics, that were previously posted in the internet being published traditionally because of it. however, there's also some type of dislike towards those types of works. there are various reasons, from the plot, to the writing style or how it was written, and etc. (and also the stereotype that comes along from a book being posted online before getting picked up by a publisher)
i really don't have a lot to say about this topic, sorry, but there is a forum on wattpad that talks about the publishing industry, publishers, editors and all the related discussion when it comes to publishing a book. there's also literary agents that comes by from time to time, doing q and a and etc.
you could also try to self-publish your work.