I haven't read the summary on purpose, since you're asking for review on the prologue only.
It doesn't really strike me as "powerful", as in emotional etc, purely because there's very standard adventure dialogue (I.E 'hold on' or ' just go!') and just a couple of shots of different characters who I don't know and therefore do not care about. It's all very abstract, which I think was your point, but there wasn't really anything unique about it, just a run-of-the-mill start to sci-fi(?) adventure. I had trouble figuring out what was happening (I still don't get it. Egyptian aliens is the only thing I gained from it? ) because of the confusing paneling & camera angles. It's good that you're going for different angles & perspective shots but I felt like with such a short prologue they just made it more confusing. The mood is dark & gritty so I think you did a good job on that. The colours are very standard western comic colours(--flat), so there's not that much to say about them. Some of the backgrounds had weird colour gradients that were just ugly colour combinations to me, but that's more a personal preference.
The anatomy is more or less okay except in the hands and faces. IMHO you should practice those more, since they stick out consistently when compared to the rest. The expressions are also off, especially the latest torso & up shot of the main character(?), in the same manner that ME: Andromeda facial animations are off. I can't honestly tell where you were going with that particular expression, I'm guessing either 'sexy' or 'hurt' but it kind of looks like she's singing more than anything. Try to google references, or just go pull faces in front of a mirror to help out with making the expressions more real.