If the story requires that I physically wreck them (which I certainly have ideas that do, as I have a slight joke with myself that someone always dies in every idea I make, no matter how innocent), then I will physically wreck them.
My characters generally tend to have physical ailments.
Emphesema and the lung and heart problems that follow, severe untrealed bleeding stomach ulcers, Severe body dysmorphia and lack of coordination caused by being shoved into a drastically different body.
An illness that's gone untreated for too long and festered,
That sort of thing.
i definitely can connect better when creators both emotionally physically hurt there characters, it makes the story more compelling to me!
for me anyone reading my work will have to read to find out 
Well my readers know Isaac is covered in bandages, the clones are as fragile as balloons, and Henri has already sustained a shard of glass through the leg along with fever and mild malnutrition. And people wonder why i call it The Rainy Days2. Cause it's gloomy. Fun, yet gloomy.
I once had this idea of this character being a complete psychopath, he would send his slaves to fight for their lives and just cure them completely(he inserted a magical stone into their bodies with 0 anesthesia ) just to torture them later by making them fight giants and monstrous being. In the story our mains, a girl and a boy fall in love, want to have kids and all that wholesome things, they would fight till the psychopath gets bored and decides to free them but he would first make sure the girl could never give birth(takes the stone out of her and then stabs her) and the dude has to watch, being unable to do anything, then the psychopath becomes a demon/god of that world.... I never did anything with the idea cause I would have to draw all those things and .... just NO!
I am not a kind writer to my characters =/ (at least I toned it down for my actual comic kao)
I try to make injuries feel impactful, whether they're big or small. My stories mostly center on non-humans, so it's important that it's clear there are still real physical dangers, and potential consequences. Though my current stories isn't too heavy, my next project goes way heavier with emotional and physical damage. I hope I can do a good job expressing that in a way that resonates but doesn't feel gratuitous!
It depends on the story, but sometimes a little violence and danger is good. 
tries to hide pike of corpses under the rug 
Uuuh, so I'm actually really bad to my characters. They always have harsh points in their backstory, lots have serious physical problems and disabilities, and lots of them die or come very close to it! I really don't pull the punches.
I once heard the writing phrase, "kill your darlings". And my own philosophy is that fir a lot characters, especially villians, the greatest honor you can do is to let them die defending their beliefs. It's way more interesting than always getting saved last minute, or worse- going back on their morals.
Although we're only a few chapters in, I can promise a lot of agony in my Current story. 1
I absolutely do.
In fact, I love characters that have different types of genetic disorders or that have disabilities, whether from birth or acquired through battle.
I feel these types of hardships, the loss of one's physical capacities brings out the real personality of a character. Imagine a great warrior who has been put into saddle as soon as he could walk, who has been leading men to battle from age 10, losing an arm or a leg. This unravels a world of possibilities for character development.
A love who abandons the warrior. His spiraling into despair. Him regaining his independence. Finding a new occupation. Urgh, I am having tears in my eyes just thinking about everything a character with a disability could do.
I love hurting my characters. Scars, noticeable impairments, gashes, all of that jazz is right up my alley.
Them coughing/spitting out blood even though the injury they receive shouldn't even cause that is so satisfying to draw.
That is such a fantastic sentiment!! I'm so glad to see another writer that understands that troubled, disabled, or mentally unstable characters are not just background noise. They have vast and deeply human stories to share with us. It's a rich well of pain and truth. I love it! Although that sounds really dark xD
But darkness is also part of life. If there was no darkness, how would we know when we experience light?
I feel that we use art to flee reality, when in fact art could be such a vehicle to sensitize people on the realities of those that share the same space as we do, that share the same oxygen but that we often put aside because they are different, because their disabilities put us ill at ease, etc.
And we forget about the stunning artists like Tjili Grant Weatherhill, Alba Somoza, Anne Abbott and so many more. All visual artists, all amazing, stunning. And all suffering from cerebral palsy. All so inspiring. When Tjili Grant Weatherhill (who is very young and yet got exposed by the Royal Watercolor Society without them knowing she had cerebral palsy) voiced that she was not disabled, just differently abled and when I looked at her art that transcends the very conception we have of color, I can just nod my head and bow in front of her talent.
I actually ended up wrecking one of the main characters of my story in the very beginning. He is undeniably a strong character, but he is far from flawless and far from being the strongest. He falls in to a coma after taking a beating and getting various cuts, bruises and burns on his body. He is eventually nursed back to health but it can be described as one of the character's most vulnerable moments in the story.
Well I don't go out of my way to do it. Only if it serves the story.
Heck, one of my demons gets stabbed with an angel's sword.
But I do have a number of characters that are introduced with injuries or illness already.
My main character, Shem 'Etzem, became more of a punching bag than originally planned. He breaks lots of bones, but since his root power involves bone needles and ossification, he can regrow them quickly.
Since I chronicle true stories, and because people get physically and/or emotionally wounded in the real world, and because people get killed in the real world, the fact that, with very few exceptions, I like everybody I write about doesn't protect them.
Most of my main characters get scratched, or bruised, or beaten, but manage to get back up no matter what and turn the tables on their opponents. I've yet to go deep with the emotional obstacles, but I may get to that as a change of pace.
Lol, yes I wreck them! The fight that's going on now is a good example https://tapas.io/episode/13368074 (rated mature episode because of harsh fight, before you click.)
I'm also a big fan of honouring old injuries, as my comic takes places over around 6 weeks ish in their world, so old injuries stay in some cases. 
