So though I understand what kind of style you're going for, but overall it ultimately comes off as messy. Having a white base with colors being applied on top is very very risky if not done perfectly, so right now the panels look a little incomplete.
Here, I cannot read the sfx at all. Though I understand you want this kind of, messy aesthetic, SFX, text bubbles, and panel borders should not be effected by these. Readability is
#1.
And example of how to make it readable.
Another problem I can see is you do basically everything with the same red line color, and similar line weights. This leads to a lot of confusion when I'm looking at these panels.
Since you're drawing the objects super messy (I can't tell what some of them are), and the main character likewise is super messy, this looks like a huge jumbled mess of confusion.
Here's a panel from Edith, which imo is probably the messiest art style I see on featured, clearly differentiates the character from the background by putting the background's lineart in a different color and a more muted palette.
I'd actually recommend going through Edith and using it as a reference for how much you should allow yourself to get "messy". In general I would recommend against the bright red outline, you should usually pick a dark outline that is less saturated than any of your main colors. It really hurts my eyes to look at.
In general, be really careful with how you place the characters. This girl kept switching from facing right to left which made this whole sequence really hard to understand. Always keep the way characters are facing consistent, and if a character's position changes, have a wide shot first to establish that they moved before doing the face close-up.
Overall I find the series pretty humorous, but I get a lot of whiplash from how much the tone can change. Right now there's a lot of random humor, but you also seem to have a sort of overarching plot that gives off a slight tone of severity, which will confuse the reader since the constant cracking up and low stakes (death is treated extremely mundane) doesn't fit the tone of an overarching plot. Try to decide if you want it to be pure comedy, or a series with a plot with humor thrown in between, and rewrite some of the scenes to either be 1. more whacky or 2. more grounded depending on what you decide to go with.
Good luck!