It's all about how you present the genre and for which audience.
I think Police Dramas can work well since the storyline gets you hook quick and as a reader, you play the game and try to figure things out. If the tension and mystery are there and it's well-paced, you are pretty much good to go (easier said than done tho'
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I feel like it's hard to pull off real-life stories, historical events or pure drama the same way movies/series do but like others have mentioned, outside of the mainstream bubble some publishers do well in those areas.
Comics (at least in the mainstream world) rely a lot on getting you excited every time the story has a chance which goes against some genre and tone.
There is this rule in manga (especially for shonen), I don't remember exactly but it goes like "you have to hype people every 3 pages" or something like that which is crazy 
Webtoon have a similar mindset, it makes it hard to write sometime.
Horror can be hard to pull off if you don't go the route of body horror.
I try to do horror and it's a pain in the ass
Horror relies on ambiances and to set those well you need frame by frame movements and audio which is what comic lacks so you need to do extra steps to get the visual and composition right to translate a similar feeling.
Pacing is hard because the reader is ultimately in control (how fast or slow they want to read) almost like in literature, you need to create rhythm with the number of panels, the amount of text etc to really let the story sink in (which I believe is necessary in all genre but may be critical for horror?).
Have yet to see a horror comic that doesn't show to much of the "monster" or the "source of evil".