It's not clear by your question if you want to do an informative comic (like tutorials, etc) or a story that is about a comic artist/writer. I going to assume it's the second, so...
You'll really want to appeal to the artistic community, so make sure you have a lot of relatable scenes. Like struggles that all comic makers have, as well as successes. But I would make sure that there's a backstory that's not directly about writing comics, like a romantic interest, some kind of rival, etc. That gives you a lot more content you can use to stretch your story out longer, an add some drama/excitement to it.
There are some anime/manga that have themes about making comics that you could check out for inspiration. "Monthly Girl's Nozaki-kun," "Bakuman," and "Comic Party" are a few that come to mind.