Crow Summer has 4 characters with major arcs, 8 named characters that appear frequently, and 10ish characters who reoccur a lot in the background. (So I'd say about 22-25 characters total. It's a pretty manageable number, I think, especially since there are really only the 4 big arcs)
Pirate Comic has 6 major protagonists, 9 major antagonists, 5 major supporting characters, 6ish minor antagonists (which appear in multiple chapters), and about 8 reoccurring background characters. (So… 34ish?? I feel like I'm missing a lot of people, but that's 34ish named characters with separate personalities and tiny arcs, so… that's a lot. There's a lot of characters. it's fun but HARD.)
I have one other major comic project which has only like… 9 reoccurring characters in the entire story. And that story is like 8 volumes long, and stretches over a time period of like 1000 years. so yeah, the cast is pretty isolated.