It's good to keep in mind that different works have different audiences. As a creator, especially with comics, probably more than novels, you don't need to target the same audience every time. A good method for finding where a comic will likely perform best, or where to pitch or sell it, is to look for "comp titles", which are other books or webcomics made in the last 10 years that have a successful following and a similar vibe to what you're making or want to make. They're really good for getting the sense of who will read a series, how popular it might be, how to market it, and you can point at them when pitching. On Tapas with Errant, my comp titles are things like Pandora's Devils and Hard Lacquer, while for the kids graphic novel I'm working on, it's things like Witch Boy and Lumberjanes.
Of course... this can make things tricky when what you're already making and passionate about is a sort of personal passion project. When rebooting Fan Dan Go into Errant, I had to consider a lot about like... how to keep stuff I liked about my old comic, and things I felt passionate about while making something that might appeal to the Tapas audience. In retrospect, due to unfamiliarity with modern webcomics, I think I leaned too far into "things I want to do" and made something that's not really optimal to ever be up there as a 50k+ subs makes me my income type comic. But.... it's not always fun or healthy to have to think of everything you make as a "product"... sometimes a little personal indulgence is necessary, and sometimes you need to just try things to see if they have an audience or not! Still, if I were to try again, there are things I'd change about the style and pacing and things to be more "Tapas-friendly", because modern webcomics are practically as bad as print for needing to laser-target your audience, but without the advantage of an editor or agent to tell you how!