Ah then in that case, it can go two ways, if you just want to serve your comics without the need for a a backend like user accounts, etc then you can spin up a template and theme and use a static site generator like Hugo (https://gohugo.io/) and just publish content that way. It's relatively straightforward and you can use Disqus to add a comment section.
The other way is to use some backend like PHP, Ruby, etc to interface with an SQL server to manage your database. Obviously this is more complex but IMO, in the end it wasn't that worth it most of the time.
If you're asking about the mechanics for the latter, you need to construct an administration area where it can accept file uploads and place it on a folder in your server. You then insert a reference of that series of uploads to the database so you can keep track of which file belongs to which episode. On the user-facing side, you then throw that into a page structured for serving them. That's pretty much the gist of it.