There's a furry community that exploded a few years back in my neck of the woods. It's not sexualized though, they attend all kinds of family friendly events. There's a whole event created for them as well as part of the community and again, it's completely family friendly. Little by little, they're opening the eyes of the people around here and it's really a positive thing.
Yes, there's a high chance that your current readers might drop you. However, that doesn't mean that you won't gain any. And who knows, because it's less of a popular genre, you might get more an audience because there's less competition.
There's definitely a market for it. Sure, there's a lot of cons, but if it's a project that you are passionate about. I say, drop the pros and cons list and just go for it. I don't come from "the big city" and to say that people can be very old fashion and a little close minded here is an understatement. But, we have respectable people who are furries and they're putting themselves out there in the community and they're accepted. There's the occasional hater, but overall... people views on what can seem a little "weird" can be changed.
So, yes, there's a lot of cons in your list, but a lot of those cons are "fears". Those fears can be overcome. You just need to take the plunge and see where it takes you. Especially if it's something you really want to do. Don't live in regret because of fear.
I say, advertise among furries. If they like it, they're read it. If they don't, then they won't read it. You win some and you lose some... it's just the way the cookie crumbles.