I really like the more vertical-inclined format of panelling (like the first two panels in chapter 2). It feels more engaging and interesting, so I think you should implement more of them into your comic.
Another thing I think the characters can use a little bit more variety in their expressions. I know that Alice is constantly distressed, but you can play with the levels of her distress; change the shape of her mouth, knot her eyebrows, make her cry. Little things like this will add a layer of depth to your art.
I hope you find this useful!