I'd have to disagree with the lack of expressiveness in realistic art, realism and styles leaning towards it can express emotion just as well. Sure, it's not excessive, mouth flying off the face expressive like simplistic styles can be, but it's there. Humans in themselves can show an array of colorful emotions. Most realism artists are just more focused on trying to get in those details, and portray their work realistically than on putting life into their work. It's not a fault of the style/base, but a fault with the artist when the characters lacks expressive emotion.
Having a more "realistic" style myself, I'd like to think my characters convey emotion with little to no issue.
To answer the question. I'm fine with whatever, but it depends on the story and how well done the style is. Not a big fan of horror stories with cutesy styles though, I never really got why people like it. Seeing some adorable character getting destroyed just isn't something I can take seriously. If you're going to have a deeper, or darker story, more complexity (in the right places) is preferred. Otherwise, I'm chill with mostly anything... As long as it's not like... Hello Kitty.
Although as a creator I like detail, visually fleshing out the world the characters live in, adding subtle things you won't see without paying attention. Yeah, that's my jam.