When it comes to the science part of sci-fi, I prefer it to be (1) as realistic as possible, with some twist to make it fiction (it's not a research paper after all), but still believable, and/or (2) just show the tech or crazy stuff as normal and part of people's everyday life. I'm usually not a fan of technobabble or random words thrown in to sound sciency, so unless I like the story a lot, I'm out
For my current comic, I tried to make the genetic explanation of people having superpowers as realistic as possible, but that was kind of cheating since I do molecular biology research in real life. Also, one of the main characters, Claudia, was inspired by a failed project I did in grad school using nanoparticles, and I thought it was hilarious how in fiction (and to conspiracy theorists), nanoparticles are this borderline magical thing that does everything, but in reality they are such a pain to work with.
Here's the thing in case someone is interested. The art starts quite rough, sorry ^^