I use the descriptions to sort of...nudge my readers in a direction I want to and sort of pull interactions out of them.
For example... I have a new character recently introduced in my comic. I want him to be the sort of character that people love to hate and...I think that's what the majority of my readers would feel about him, regardless of what I put in my description, but by kind of encouraging my readers to hate him in the descriptions, hating him has practically a meme among my readers now, with them literally making a song dedicated to what a douche he is. :'D
It's 100% the result I wanted, and while I think everyone would "love to hate him" even if I left my descriptions blank, I've definitely got readers that are commenting every page to just tell me how much they hate him now because I think they see that's kind of what I want them to do.
Honestly... I don't think ever "inappropriate," in my opinion. Even if it's just a "I like this page," I've always had a description on every page of my nearly 200 page comic and nobody's ever really ever thought less of it because of them, no matter how long or short. No matter what, people can still just ignore the descriptions if they so desire. And those who don't are probably just either completely neutral to descriptions, interested in what you have to say, or eager to respond to them.