As a reader, I tend to devour the series I start to read. I easily get engulfed by a story if I fall in love with it, so I want to read more and more in fast, full immersione, lengthy sessions. I can't help it, I'm greedy... But that's why I prefer to read series that already came to and end. I'm very bad at waiting for weekly updates, both long or short. If I have to choose, according to what I said, I'd prefer medium or long updates. Most of my nerdy friends are like me, to be honest, and I think this applies to the average reader who's unaware of what happens behind the scenes.
As an artist, you already know the problems and issues of working alone on such a hobby. The same goes for me but I also want to keep in mind the needs of the reader, that's why I'm working on a huge buffer before start posting (at least 1 year worth, if I can resist the temptation to anticipate it). I'd like to submit 4 vertical pages a week. Not too many, not too little. It's a lot of work and exposure will be limited but I think that updates with multiple pages can help appreciating more a story: you can remind the readers what happened before with brief mentions and you also have the time to fully develop a scene.
Besides, many users in this forum say that you shouldn't publish webcomics for the numbers, the exposure, the fame. That you should do it because it's something you love. I do believe it too so, to me, it's not such a big issue if I don't appear in the Fresh page as often as others. I'm quite convinced publishing multiple pages a week creates such an interest in the story so much so that it pays back the sacrifice.
At the end of the day, it's your choice.
My choices are usually wrong, hehe. But I took this decision and I can't wait to implement it and see what happens. But, right now, I must work hard to make it true. The anticipation is enough to keep me motivated.