Having had to make pages to keep my schedule up during a nightmare house move where I had a couple of nights in a row of maybe 4 hours sleep tops, I can say I can do it, but do not recommend doing it and would be happy to never have to do it again.
When I did pages last week with a banging headache due to a head cold, I managed to get them done, but then noticed later, I'd done a character's eyes the wrong colour and not even noticed til I after uploaded it. Those are the kinds of little errors that slip through when you're exhausted, plus just generally sloppy inking and colouring, or on the writing style, the writing tends to be a bit uninspired or rambly.
Better to get some rest and make sure you're in good condition if you can!