Sort of. When I'm doing long shots, I'll do a simplified style with shorter proportions (like 4-5 heads or something instead of 7), and I'll simplify eyes to dots or cartoon circles. I'm also working on some cutesy 4-koma drawings.
But I haven't done full metamorphosis into someone else's style yet. I do love that one comedy trope of a character suddenly having like Fist of the North Style craggy features and high contrast, though.