My current comic tends to parody major religions, but I forget sometimes that because I've substituted a lot of my own chicken-related mythos/terminology/traditions with a humorous twist, then it really doesn't bother me all that much.
There are some, uh, awkward moments between some human characters (and some coming up) that I tend to worry about, but I try to depict them humorously in a it's-not-what-you-think kind of way (racial, or it appears that way) I kind of base humor on broad stereotypes, but of coarse the characters themselves tend to override them, or at least a few of them. Beginnings are always kinda awkward - or maybe that's just something about my personality, but my hope is over time that awkwardness fades and you get to know the characters as they develop, albeit slowly (story is kinda slow, I admit).
Here's a moment out of context that illustrates what I mean:
Alec(basically Col Sanders): So, Aldi, white or dark?
Aldi(his African-American female assistant): Is he serious?
Alec: Or do you even like chicken?
Yeah, I feel like I'm walking on eggshells, but no harm no fowl. There's bound to be someone out there that will get overly-offended, and I would understand, but it's solely meant for comedy.
Oh, on another note, I want to make a furry noir series that features NSFW, super-rated-M erotica, wanton violence and just plain vice. Even a human-doggo relation O.O ...
Not ashamed of that one, cause I'm gonna publish it under a different name/profile(don't want to soil this one too badly, Lol!) But it'll take a couple years to get the art done and I gotta do more--research.
I can't wait!