My parents know I'm drawing a comic, but I've not shown it to them, and they don't ask. They don't see me drawing very often (I live on a different continent) so if I don't bring up the subject, they don't think of it. I'm neutral toward them reading it, so I make no effort to show it or conceal it to them. They saw a few panels.
My spouse recently edited my first chapter (I have yet to implement the changes), and the feedback was amused but rather negative, so I'm not sure if I'll ask editing for the next chapter (apparently, my characters are too North American for the fantasy setting, my main character too bratty and the story too difficult to understand. Thanks
).
I did not show it to any friends locally because I'm not a very trusting person and I'm too afraid that it will be shared to the wrong persons. I'm still adapting to living in a place considerably more judgmental that where I was living before, so I don't really want to add new problems.
I did show it to a selection of old friends, internet friends etc., they are generally uninterested by comics in general, so they don't really care.
So I'd say the interactions I have with family and friends about my comic are very limited.