No wrong answer. It depends on the art style you want to go for. Instead of asking yourself "Do I want to do it?" ask yourself "What do I want it to look like?"
See for myself since day 1 I wanted my comic to be B&W but shaded, I just wasn't confident enough in my shading yet. I'd try it but it would look odd to me so I'd publish without it. Once I did a page where it didn't look weird to me-
(This page)

I began publishing with every page (Unless characters were really small and far away) with shading.
But that was my goal from the start. I think you're asking yourself the wrong questions. "Can I get away with..." or "Is it appropriate..." No, man. What is the look you're going for? That's the question that matters most. If you want it to be shaded then practice, practice, practice. If you want the images to use bold colours and negative space more then that's already a really good look, too.
Also there's no rule that says you can't do both. Maybe punctuate a very dramatic moment with shading? Your call.