Honestly, this problem has stopped projects in their tracks for me. Just thinking of all the constant criticism I could get.
I think a good thing to do, with any social anxiety problem, is look at how you perceive others. Like, you don't notice or care about things about other people that you get anxious they're judging you for. Nobody's gonna get angry about your anatomy slip up there, or shout about how terrible your plot is. In fact, from what I've seen here, there's very rarely backlash in general. When people don't like something, they just don't subscribe, or don't read.
But also, as someone dealing with this anxiety, I know understanding that doesn't always work. I'd honestly say, fuck all of them, you're making this comic for you and you're gonna enjoy it even if they don't - and some other people will, too. The best way to deal with anxiety for me is to just give zero fucks. It's hard - especially since deep down you really really really really care - but just try to convince yourself, see how it goes.