i have dual monitors and a laptop- the laptop is mostly for binge watching avatar and then airdropping my files onto so i can tote whatever i'm working on with me.
on my primary monitor, which is like 32 inches and great for drawing on, i run whatever program i'm working in (illustrator, photoshop, unity, dreamweaver etc). then on the second, smaller monitor i like to keep reference images, information, and any correspondence from commissioners/work so i can look at what i'm working on and what i'm working from at the same time without needing to flip through programs