That was a very tricky question for me when I started my webcomic
It actually has different characters with different sexes and sexual orientation, including gay, hetero and trans characters.
The trick is that comics started with gay couple. And this couple is the most popular at the moment. That made people think my comics is BL. I didn't really consider that as a proper genre because of the other couples but still added "BL" to hastags just in case. But not to genre.
I don't think BL genre is something bad, I honsetly enjoy it. But I personally can't stand the cliches many BL comics are filled with. The main is something like "Here we have blond and brunette main heroes, they hate each other, but then one of them saves another's life, they sleep together and fall in love forever". Possibly that's the thing that disgusts many other people too, but the genre itself isn't bad. There are some deep and strong stories too
Then there was hope to have two genres for a comics, so I was really happy because I could use both Romance and LGBT genres. The hope was lost and I had to choose only one.
Even though my comics obviously suits for LGBT genre, I still preferred Romance. Just because of intuition I guess. I think in my story I focus mainly on relationship psychology, deep feelings and personalities. And only after that I think of my character's sexual relationships. And I guess that better suits for Romance
But if for example I was focusing on my character's sexes, like it was MOST important to show "he suffers so much because of his gay nature and here we have trans who can't properly make friends because people don't accept him, etc." then I'd definitely choose LGBT (BTW this also means LGBT story doesn't have to be romantic). I still touch these themes in my Romance story, I just don't focus on them too hard. But if I could use second genre, I would definitely use LGBT
However, on Webtoons I use "Romance" and "Slice of life" and guess these two suit my comics well too